Enantioselective synthesis of 4-aminopyrrolidine-2,4-dicarboxylate derivatives via Ag-catalyzed cycloaddition of azomethine ylides with alkylidene azlactones.
نویسندگان
چکیده
A catalytic highly enantioselective silver-DTBM-segphos catalyzed cycloaddition of α-iminoesters with alkylidene azlactones is reported. This procedure provides an effective access to 4-aminopyrrolidine-2,4-dicarboxylate derivatives with high diastereo- and enantioselectivity.
منابع مشابه
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ورودعنوان ژورنال:
- Chemical communications
دوره 49 41 شماره
صفحات -
تاریخ انتشار 2013